This course will be of genuine benefit to anyone desiring a basic understanding of the adverse effects of drugs and other chemicals in humans.

COURSE DESCRIPTION //
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The ultimate "safety" of any substance (drug, food additive or other consumer product), whether naturally occurring or "man made", is based on prescribed toxicological investigations. 

Given its importance to so many fields of endeavour - including environmental (indoor and outdoor) science, occupational health, food science and forensic science, in addition to drug development - it could be argued that all life science graduates should have an understanding of at least the basic tenets of toxicology. This, of course, is not the case; even recently graduated physicians, pharmacists and other health professionals have studied little, if any, toxicology per se. As the distinguished British toxicologist, Francis Roe, pointed out in a foreword to a book on toxicology: "It is a fact of life that the disciplines of greatest current importance are the least well represented in terms of university chairs and departments. Toxicology falls into this category." 

With an aim of instilling an appreciation for the simple, but key, concept that "the dose makes the poison", course participants will receive sound instruction in the varied and interesting fundamentals of modern toxicological science. The course will be taught in a didactic, but informal, manner with a short self-assessment 'quiz' upon completion of each learning block. 

PARTIAL COURSE CONTENTS //
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• History and terminology 
• Routes of exposure 
• Physiochemical & biological determinants of toxicity 
• Dose-response concepts (e.g. LD50, etc.) 
• Toxicity testing procedures 
• Acute, subchronic and chronic toxicity 
• Toxicological observations in living organisms 
• Maximum tolerated dose & "effect levels" (e.g. NOAEL)
• Neurotoxicity
• Teratology
• Immunotoxicity 
• Toxicity to the "organs of elimination" (liver & kidney)
• Xenobiotic metabolism (biotransformation) 
• Mutagenesis and Carcinogenesis
• Toxicokinetics (single and multiple doses) 
• Procedures for estimating safe human doses
• Literature and online sources of toxicological information 

FALL VENUE //
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October 23 - 24, 2008 (NOTE: Two-day Event)
TraveLodge Hotel Toronto Airport 
925 Dixon Road 
Etobicoke  Ontario 
M9W 1J8

To register for this course CLICK HERE.